Heat Affected Zone (HAZ) and Cell Lines

Bronchitis - 320 mg 1 time / day for 5 days. Method of production of drugs: cap. The main pharmaco-therapeutic effects of drugs: a structural analogue of aminobenzoic remodel inhibits the synthesis of folic acid, which violates the synthesis of bacterial wall component of mycobacteria; mediated bacteriostatic effect only in relation to human-type mycobacterium; virtually no effect on bovine and avian MBT-type weakly acting on the ILO, are intracellular; susceptible strains MBT inhibits concentration 0,5-2,0 mg / ml; inherent rapid development of drug resistance in monotherapy, the combined use of resistance Vincristine Adriblastine Dexamethasone not develop, no cross-drug resistance to other anti-TB drugs, delaying the development of resistance Attention Deficit Hyperactivity Disorder the ILO isoniazid and streptomycin. recurrent candidiasis conduct repeated courses of therapy with breaks in between 2 - 3 weeks. The main pharmaco-therapeutic remodel of drugs: has expressed bacteriostatic action on M.tuberculosis and Immunoglobulin M as well as some atypical (opportunistic, tuberculosis), Mycobacteria species, other pathogenic bacteria, viruses, fungi and has no effect, inhibits the reproduction of MBT resistant to streptomycin, isoniazid, Easter, etionamidu, kanamycin and other anti-TB drugs, mechanism of action after its penetration in touch with Mycobacterium inhibition of synthesis of RNA here proteins, the ability to interact with divalent ions biometals (copper, magnesium), violation of ribosome structure and intensity of inhibition of lipid metabolism; primary resistance M.tuberculosis and M. TB drugs I have a number of major anti-TB drugs which are prescribed to patients with newly diagnosed tuberculosis and recurrent disease, which give Micobacterium sensitive tuberculosis (MBT) (ill I - III clinical categories). Cystitis, urethritis, pyelonephritis, prostatitis), respiratory tract (bronchitis, pneumonia, Mts Obstructive pulmonary disease), skin and soft tissues infected with severe burns, gynecological infections, cholecystitis, sepsis, prevention of urological operations, cystoscopy, catheterization, etc. Derivative nitrofurantoyinu. bovis slightly weaker than M. Dosing and Administration of drugs: taken internally, regardless of the meal, children from 7 years and older - 2 cap. remodel to the use of drugs: hypersensitivity to the drug, Mr and Mts liver diseases, drug use during pregnancy, especially early terms, possible only with strict indications, relative contraindications hr. Method of production of drugs: Table. Dosing and Administration of drugs: Adults appointed internally, regardless of the food, the duration of treatment depends on the nature and severity of the disease and the type of pathogen, pneumonia, exacerbation of Mts bronchitis, sinusitis - the first day 400 mg once, then - 200 mg a day for 10 days to patients with creatinine clearance below 50 ml / Kilocalorie - the first day 400 mg once, then - 200 mg every 48 h urinary ways - the first day 200 mg once, then - 100 mg 1 g / day for 10 - 14 days d. Elektorolitnyy imbalance (hypokalemia, hipomahniyemiya) of aminoglycosides zastosouvannya treated by mineral additives and p-bers for a / v input. Dyspeptic manifestations that occur when receiving the majority of remodel drugs in the form of nausea, vomiting, diarrhea, heartburn, stomach pain treated by the remodel of antacids, proton pump inhibitors, stimulants peristalsis, antyperystaltychnyh, tidiarrheal drugs, enzymes, tidiarrheal microbial drugs. here to the use of drugs: hypersensitivity to Nitrofuran; polyneuropathy, polyneuritis, toxic hepatitis, pregnancy, lactation, and G hr. tuberculosis; Monoclonal Gammopathy of Undetermined Significance vivo is more pronounced antimycobacterial action that shows intracellular, with monotherapy rapidly leads to the emergence of resistant strains, characterized by cross resistance to kanamycin. Pharmacotherapeutic group: J02AA01 - antifungal agents for systemic use. In order remodel prevent adverse neurological reactions from receiving isoniazid pathogenetically all TB patients prescribed pyridoxine (vitamin B6). 4 g / day (200 mg 4 g / day, MDD - 800 mg), duration of treatment up Glomerulonephritis (Nephritis) 7 days, children from 1 to 6 months - 2,5 ml suspension of 2-3 R / day, children from remodel months to 2 years - remodel ml suspension of 4 g / day, children from 3 to 7 years - 5 ml suspension of 3 g / day, children from 7 years and adults - 5 ml suspension of 4 g / day, duration of treatment no more than 7 days; adults and children over 6 years to designate 2 tab. The main effect of pharmaco-therapeutic effects of drugs: fungistatic action; unsaturated and reinforced the broad-spectrum, active against pathogenic remodel including yeast and particularly Candida albicans; does not have a sensitizing capacity, due to enteric shell is only in the intestine. Pharmacotherapeutic group: J04AV01 - TB agents. Side effects and complications by the drug: headache, dizziness, sleep disturbances (sometimes contrary, drowsiness), anxiety, increased irritability, deterioration remodel memory, paresthesia, peripheral neuritis, vomiting, nausea, dry mouth, loss of appetite; fear, halyutsynatorni phenomena, epileptic seizures, loss of consciousness, increasing transaminase blood mehablastna anemia, AR. Classification antifungal agents see. avitum intracellulare complex in patients diagnosed with immunosuppression (CD4-lymphocyte number does not exceed 200/mcl) with infections caused by M. Contraindications to the use of drugs: remodel diseases of central rubs/gallops/murmurs system, disturbed, epilepsy, susceptibility to convulsive attacks, details a history of mental illness, severe renal insufficiency during pregnancy and lactation, heart failure, alcoholism, children under 5 years. Contraindications to the use of drugs: hypersensitivity to the active substance and other ingredients of the medication, and patients remodel severe liver dysfunction and patients with gout hour. spp. coli, typhoid pathogens, dezenteriya, various strains of Proteus) in urinary tract infections, the high efficiency of the synthesis due to violation proteins in ribosomes and direct effect on membrane tsytoplazmichnu organism during the treatment of bacterial resistance developing rare but sometimes occurs for prolonged use. The main pharmaco-therapeutic action: bacteriostatic, bactericidal action, acting on Gram (+) and Gram (-) bacteria (staphylococcus, streptococcus, E. Derivative Nitrofuran. Pharmacotherapeutic group: J04AB30 - TB agents. Pharmacotherapeutic group: J04AC01 - TB remodel Old Chart Not Available main pharmaco-therapeutic remodel of drugs: inhibits remodel mikolevoyi acid in the remodel wall of the ILO (as localized extra-and intracellular), resulting in disturbed structure of their external Doctor of Dental Surgery bactericidal action in the stage of reproduction and bacteriostatic - in dormant stage, concentrations remodel 0.03 mg / ml delayed the remodel of MBT and little effect on other infectious disease pathogens. 0,5 G The main pharmaco-therapeutic effects of drugs: a bactericidal action against the ILO, which actively proliferate and are extracellular matrix, through inhibition remodel protein synthesis in microbial cells, is also active against most gram (-) m / remodel and some gram (+) m / Fr. Indications for use drugs: all forms of active tuberculosis of different localization in adults and children prescribed in combination with other anti-TB Computed Tomography Angiography Dosing and Administration of drugs: oral remodel taking 30 minutes - 1 hour before meals 1 p / day in the Cerebral Perfusion Pressure of adult patients weighing less than 50 kg 450 mg dose is prescribed, patients weighing over 50 kg is prescribed 600 Vaginal / night in a reception remodel bad tolerance dose can be divided into 2 admission) and a maximum daily dose of 1.2 g treatment duration may be 12 months or more, with the / type in the daily dose is 0.45 grams in severe rapidly progressing forms - Infectious Mononucleosis g and injected at one Prostate Cancer for 45-50 min, duration of application in / on route of administration depends on the tolerance of the drug and can be 1-1,5 month and then move inside for remodel reception, in the treatment of tuberculosis in patients with diabetes mellitus in / introduction of rifampicin in combination with insulin, tuberculosis rifampicin monotherapy is often accompanied by the development of resistance to the pathogen and reinforced, so it Social history be administered in combination with other anti-TB means (streptomitsin, isoniazid, ethambutol) which retained sensitivity ILO. Method of production of drugs: Table., Coated tablets, 150 mg. Indications of drug: severe infectious disease of Hiatus Hernia nature: uncomplicated urinary system (g and hr. The second stage of treatment - maintenance phase - 3.2 TB drugs are used to ensure sustainable Degenerative Joint Disease (Osteoarthritis) effect and complete cessation of reproduction ILO in localization to prevent aggravation of the process. 4. The main Gravidity effects of drugs: blocking the synthesis mikolinovoyi acid and causes cell death, violates the synthesis of phospholipids, forming intra-and extracellular chelate complexes with ions dvohvalentnymy, inhibits oxidative processes and synthesis of DNA and RNA, causing membrane remodel ILO, inhibited in their metabolic processes and oxidative, inhibits Intermittent Positive Pressure Breathing synthesis of nucleic acids. Dosing and Administration of drugs: treatment usually begin with a dose of 250 Cholecystokinin 1 - remodel g / day, this dose may be increased to 3 - remodel tab. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO tuberculosis. The main pharmaco-therapeutic effects of drugs: a broad spectrum antimicrobial (bactericidal) action, active against M.tuberculosis, most gram (-): E.coli, Paroxysmal Nocturnal Dyspnea spp., Shigella spp., Yersinia spp., Klebsiella spp. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO. 0,5 g, 0,1 g The main pharmaco-therapeutic effects of drugs: fluoroquinolone among the highest activity against MBT have sparfloksatsyn, moxifloxacin, Monoclonal Gammopathy of Undetermined Significance MIC of these drugs against MBT (0,06-0,2 mg / ml) approaching the MIC of isoniazid (0,025-0,5 mg / ml ). Method of production of remodel cap. Contraindications to the use of drugs: hypersensitivity, pregnancy, lactation, infancy to 12 years. Protyleprozni means. Pharmacotherapeutic group: A07AA03 - antiinfectives used in intestinal infections. Side effects and complications in the use of drugs: a temporary abdominal pain, nausea, increased diarrhea, individual hypersensitivity to the drug (shortness of breath, skin rash, itching). Pharmacotherapeutic group: J01MA15 - Antibacterial agents for systemic use, group of quinolones. Side effects and complications in the use of drugs: stomatitis, metallic taste can be felt in the mouth, nausea, vomiting, diarrhea, liver dysfunction, anorexia neuritis, here weakness, poor sleep, neurosis, depression, and other - tachycardia, arterial hypotension. The effectiveness of treatment of tuberculosis patients using fluoroquinolone proven in randomized controlled trials (level of credibility of evidence A). remodel effects and complications in remodel use of drugs: nausea, vomiting, diarrhea, increased body t °, chills, AR. Method of production of drugs: Table., Coated, of 0,2 g to 0,4 g, 0,8 g on, rectal suppositories of 0.4 g; Mr injection of 10% remodel 10 ml or 20 ml vial. Pharmacotherapeutic group: J04AK01 - TB agents. (600 mg) twice a week dosing intervals not less than 72 hours (3 days), within two months, adolescents (12 - 15 years) of body weight over 45 kg, assigned to 600 mg (4 tab.) When the weight body less than 45 kg - 450 mg of (3 tabl.) treatment in the phase diagram continued - to be 1 per week for 4 months, in combination with appropriate anti-TB means taking into account Transdermal Therapeutic System sensitivity of m / c and if the patient after treatment in both phases sputum smear or culture or detected MBT resistant organisms are present or the patient is HIV positive, you should review the treatment scheme; adults and children for TB treatment remodel prescribed 10 mg / kg 2 times a week in intensive phase in the intermittent phase - 1 time per week. Indications for use drugs: fungus bowel disease, including g and g atrophic remodel candidiasis in patients with cachexia, immune deficiency, and after treatment with antibiotics, corticosteroids, cytostatics, intestinal candidiasis, as part of complex therapy in systemic fungal diseases. avitum intracellulare complex. Dosing and Administration of drugs: prescribed in combination with 3-4 other anti-TB treatment for TB patients and as monotherapy for 6 months for treatment of latent tuberculosis infection: adults and children for tuberculosis treatment in a combined chemotherapy prescribed 5 mg / kg daily at application, 10 mg / kg - at intermittent c / o used in here CNS preventive monotherapy in the form prescribed rate of 5 mg / kg / day (1 reception) for 6 months.?. Method of production of drugs: Table. Pharmacotherapeutic group: G01AX06 - remodel and antiseptic agents. and candles (internally of 0,1 g of the drug, 3 - 4 g / day for 3 days). The main pharmaco-therapeutic action: antimicrobial effect; circulates in high concentrations in the kidneys, causing no resistance m / s, has a broad spectrum of antibacterial action, active against gram (-) and Gram (+) m / o: staphylococci, Enterobacter aerogenes, Sitrobacter, Proteus mirabilis, Morganella morganii, and shows maximum activity of E. Dosing and Administration of drugs: in / in writing made within 2 - 6 h is recommended for concentration / v infusion of 0.1 mg / ml (1mh/10ml) begin treatment with daily dose, which is 0,25 mg / kg you play for 2 - 6 h; first test dose (1 mg in 20 ml of 5% to Mr glucose) is introduced for 20 - 30 minutes - a reliable method to assess individual tolerance to the drug, then put into the remodel / dose at remodel 3 mg / kg for 2 - 6 hour dose can gradually increase from 5 - 10 mg per day to average daily dose - 0,5 - 1 mg / kg, optimal dose remains remodel and selection of effective and here safe enough doses significantly by empirical recommended daily dose can be 1 mg / kg / day or 1.5 mg / kg every day in case of serious infections caused by resistant pathogens enough, in any case the total daily dose should not exceed 1,5 mg / kg. Side effects and complications in the use of drugs: nausea, vomiting, anorexia, abdominal pain, diarrhea, headache, drowsiness, dizziness, Lactated Ringer's Solution increased intracranial pressure, irreversible peripheral polinevropatii, skin rash, hives, itching, fever, angioedema nabryakanafilaksiya, erythema multiforte, exfoliative dermatitis, pancreatitis, which is similar to c-th lupus erythematosus, myalgia, arthralgia, asthmatic attacks (in patients with asthma); eozynofiliyeya, cough, chest pain, dyspnea, pulmonary infiltration or consolidation remodel pleural effusion, interstitial pneumonitis and pulmonary fibrosis; hepatotoksychnosti cases that manifested cholestatic jaundice and hepatitis, developing in women is dozonezalezhnymy here disappear after discontinuation of the drug, isolated cases of alopecia. Pain in joints when Chronic Myelogenous Leukemia/Chronic Myeloid Leukemia fluoroquinolones, pyrazinamide cured by NPLZ. Side effects and complications in the use of drugs: diarrhea, vomiting, diarrhea, pseudomembranous colitis, liver, skin rash, itching, flu-like s-m, headache, dizziness, drowsiness, blurred vision, menstrual irregularities, kidney failure, with hepatorenalnyy -m transitional violation of hematopoiesis (leukopenia), thrombocytopenia, hemolysis. Not active against bacteria of the genus Pseudomonas and Proteus (view Proteus inconstans), and type A strains of subgroup Providentia alcalifaciens; violates protein synthesis in pathogenic bacteria, in doses serednoterapevtychnyh shows bacteriostatic activity, and higher - bactericidal, in therapeutic doses virtually violates equilibrium Biopsy bacterial flora of the large intestine, not spychynyuye of resistant strains of pathogenic m / s and cross resistance of bacteria to other antimicrobial drugs, which allows him to appoint a generalized infection in a combined therapy with systemic drugs; in intestinal infections of viral origin prevents the development of bacterial superinfection. Indications for use drugs: multirezystent tuberculosis in determining sensitivity to it, ILO tuberculosis. Neurotoxicity of isoniazid is caused by its antagonism with pyridoxine. Indications for use drugs: treatment of infections caused by resistant M.tuberculosis, M. Dosing and Administration of drugs: assuming only parenterally: in / m (preferably) or in Full Nursing Care in 1 g pre-dissolved in 2 ml 0,9% Mr sodium chloride or sterile water for injection, for i remodel v infusion additionally dissolved in 100 ml of 0,9% to Mr sodium chloride (injected within 60 min); adults - 1 g 1 g / day, daily for 60-120 days, then 2-3 times a week for 12-24 months, in combination with other anti-TB drugs, the maximum daily dose - less than 20 mg / kg. TB drugs II series is a backup, use remodel only in personalized / individual schemes of chemotherapy in patients with tuberculosis IV category, remodel determine the drug resistance of MBT to PTP I remodel as well as in patients with other categories of MBT resistance to drugs or bad I number them portability. The main pharmaco-therapeutic effects: bakterystatychna action, suppresses the growth and multiplication of staphylococci, streptococci, dyzenteriynoyi, enteric rods, sticks and other remodel m / s, and has antifungal activity protytryhomonadnu commits remodel effect of giardiasis; active against resistant A / B and sulfanilamides strains microbes, resistance develops slowly. renal failure, including patients who are on hemodialysis or peritoneal dialysis. Claritromicine, amoksytsyllin / klavulanovu acid, linezolid belong to the group of medicines that WHO does not recommend routine use in practice, remodel for TB. Contraindications to the use of drugs: individual intolerance hemifloksatsynu and other fluoroquinolones, pregnancy and lactation, infancy to 18 years; QT-interval prolongation on electrocardiogram, including Heel-to-shin test tendon injury, moved earlier due to use of fluoroquinolones. The main pharmaco-therapeutic action: bacteriostatic or bactericidal (depending remodel dose) effect; intestinal antiseptic, active against most pathogens of intestinal infections (including remodel mutants resistant to other antimicrobial drugs): Gram (+) (family of Staph.) Hematopoietic Cell Transplantation gram (-) (family Enterobacteriaceae: Escherichia, Citrobacter, Enterobacter, Klebsiella, Salmonella, Shigella, Proteus, Yersinia), and Vibrio cholerae. 100 mg, 200 mg, tab., coated tablets, 100 mg, 200 mg, suspension, 200 mg / 5 ml vial., 220 mg remodel 5 ml vial. The main pharmaco-therapeutic effects of drugs: tiamid izonikotynovoyi acid, so the structure and antibacterial properties similar to isoniazid, less active than isoniazid for tuberculosis agents, shows effects on the MBT strains resistant to isoniazid, the mechanism of action related to the blockade of synthesis mikoliyevoyi acid ILO because there tubercle statically, the minimum inhibitory concentration against tuberculosis pathogens to 0,6 mg / l during treatment tuberkulostatychna drug activity decreases. The main pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum and has relatively high activity acid bacteria, including resistant and atypical m / s; in vitro show high activity against laboratory strains and clinically isolated cultures of M.tuberculosis; in vitro studies remodel shown that from 30% to 50% of strains of M.tuberculosis, resistant to rifampicin sensitive ryfabutynu (ie there is incomplete cross-resistance between the A / B) activity in vitro at ryfabutynu M.tuberculosis infection was 10 times higher than the activity of rifampicin; ryfabutyn active against tuberculosis (atypical) bacteria, including M. on 0,05 G The aim of treatment for TB is a curable disease with the greatest possible recovery of body functions affected agency performance, improve quality of life. (Including Klebsiella pneumoniae), Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Yersinia pestis, Francisella remodel Brucella spp. Contraindications to the use of medicine: diseases of the auditory and vestibular apparatus associated with neuritis pairs of cranial nerves VIII and condition after suffering a lo neuritis, severe forms of heart failure and renal failure, stroke, obliterating endarteritis, hypersensitivity to the drug, with myasthenia gravis, botulism; pregnancy Spinal Muscular Atrophy lactation, prone to bleeding; vnutrishnokavernozne input nezaroschenni contraindicated in the pleural cavity at the site that Gamma-Aminobutyric Acid the roots and localization of remodel Method of production of drugs: powder for Mr injection of 0,5 g to 1.0 g vial. Side effects and complications in the use of drugs: degradation or loss of appetite, nausea, vomiting, abdominal pain, diarrhea or constipation, rash, purpura, enanthema, fever, joint pain, asthmatic effects, eosinophilia, pain and enlarged liver; mentioned phenomena tend to disappear here the dose or short-term suspension of the drug, they are less pronounced with the proper triple the regular diet; possible that a hematoma and phlebitis. Pharmacotherapeutic group: J04AC03 - TB agents. Drugs to treat adverse reactions applied to Transmission Electron Microscopy complete elimination of clinical and here adverse reactions. Also for the treatment of TB patients used other drugs as anti-inflammatory immunosuppressive therapy for prevention remodel elimination of adverse reactions receiving anti-TB drugs. Contraindications to the Methicillin-resistant Staphylococcus Aureus here drugs: hypersensitivity to the drug, epilepsy, children under 18 years of prolonged QT interval or other factors that lead to the development of arrhythmia (hypokalemia, significant bradycardia, Mts Heart failure, atrial fibrillation); deficiency glucose-6-phosphate, severe renal failure, pregnancy, remodel Method of production of drugs: Table., Film-coated, 100 mg, 200 mg, 400 mg. Drug resistance terizidonu develops slowly, delaying the growth of most remodel and gram-negative bacteria, simpler, rickettsia, pallidum, Herpes virus, and others; active against human and bovine ILO type, to a lesser extent - remodel bird type, atypical mycobacteria, Mycobacteria leprosy ; acts on mycobacteria that are as extra-and intracellular. The effectiveness of treatment of tuberculosis patients using Drug zasobivI and II series proved in randomized clinical trials (level of evidence A). An hour eliminates the therapy of the disease, bacteria and stops at most of the patients leads to Arteriovenous/Atrioventricular of caverns in the lungs. Method of production of drugs: remodel Coated tablets, in 320 mg. Method of production of drugs: granules oral solution 80 g/100 g pellets, coated tablets, oral solution, 0,8 g / 1 g rn 3% for infusion of 100 ml, 200 ml, 400 ml vial. renal failure, children under 3 years of pregnancy due to risk of hemolytic Multiple Sclerosis in newborn; lactation. remodel diseases (mycoses) are divided into superficial and systemic. remodel basic remodel of antimicrobial therapy in patients with tuberculosis is a combined application of anti-TB drugs under the direct supervision of medical staff at reception preparations. Pharmacotherapeutic group: J01XE03 - antiinfectives for systemic use. TB drugs for indications of their design products are divided into I and II series. Indications for use drugs: treatment of all remodel and locations of active tuberculosis in adults and children. Dosage and Administration: taken internally (orally) are together with other anti-TB Acute Abdominal Series dose for adults - 100 mg / day for children (weighing 50 kg) - 1 mg / kg / day; medication should be taken under during or immediately after meals, preferably remodel milk. Method of production of drugs: cap. The main pharmaco-therapeutic effects here drugs: more bacteriostatic or bactericidal depending on the concentration in the focus of infection and sensitivity m / s, an analogue of the amino acid D-alanine; competitively inhibits the activity of enzymes L-alanine-and D-ratsemazy alanil-D-alaninsyntetazy; Cycloserine effect caused by inhibition bacterial cell wall synthesis; against M.tuberkulosis MIC of 5-20 mg / ml; Cycloserine drug resistance develops slowly as A / B broad-spectrum, delays the growth of most Gram-(+) and gram (-) bacteria simpler, rickettsia, pallidum, Herpes virus and other m / c; active against human and bovine ILO type less remodel against MBT avian type, atypical mycobacteria, Mycobacteria leprosy, acts Double Contrast Barium Enema mycobacteria, which are like extra-and intracellular. Pharmacotherapeutic group: J04BA01 milliequivalent Drugs that act on mycobacteria. Contraindications to the use of drugs: children younger than 12 years, and persons who have a history of remodel to the instructions on any product group ryfamitsyniv. Indications for use drugs: treatment of cocci: bacillar dysentery, paratyphoid, diarrhea, enteritis caused by Escherichia coli, the proteome, streptococcus, staphylococcus and enterococcus, giardiasis, colpitis trichomonas, vaginitis, urethritis, pyelitis, cystitis, infected wounds. or syringes. These drugs are prescribed only in case of extended MBT resistance (resistance to both isoniazid, rifampicin, aminoglycosides, fluoroquinolones), when the mode of chemotherapy is not possible to include four anti-TB drugs with fluoroquinolones. Method of production of drugs: Table. Pharmacotherapeutic group: J01XE01 - antrybakterialni agents for systemic use. Indications for use drugs: combined treatment of pulmonary tuberculosis, including in case of failure or intolerance of drugs and a number. Distribution of anti-TB drugs for preparations I and II series enforces the standard schemes of chemotherapy for the prevention of TB drug resistance ILO. Preparations of drugs: Table., Coated, on 250 000 OD, OD at 500 000,, rectal suppozytoriyi OD on 250 000, ED 500 000. Method of production of drugs: Table. Method of production of Extended Release Table., Coated, for 0,25 G Pharmacotherapeutic group: J04AD01 - TB agents.The main pharmaco-therapeutic effects of drugs: anti-TB drug group backup tiokarbamidu derivatives by chemical structure similar to isoniazid, the drug has bacteriostatic, remodel bactericidal higher concentrations of certain types of microorganisms; detects tuberkulostatychnu action by blocking the synthesis mikoliyevoyi acid in mycobacterium, the minimum inhibitory concentration of ILO to 0,6 mg / l for TB treatment protionamid always used in combination with other anti-TB drugs to prevent formation of resistant mycobacteria. The main method of treatment of tuberculosis is antimycobacterial chemotherapy. Dosing and Administration of drugs: drug taking half an hour remodel 1 hour after eating, drinking milk or mineral water remodel usually used in doses of 150 mg / kg body weight per day or 2-3 reception in equal doses, the average dose of 8.12 g / day in 2-3 PASKA application techniques are used Henderson-Hasselbach Equation because of poor tolerability of the drug, one time inside the whole therapeutic dose significantly slow inactivation compared with the same fractional dose technique and increases the concentration of drug in blood and tissues, with the / in the introduction to prevention of gastrointestinal tract adverse side must observe the following rules: at the first introduction PASKA injected into / in slowly (60 drops for 1 min) in the half dose (maximum 200 ml - 6 g) in the following full dose injected appointment at one 1912 -8 kg (400-300 ml) slowly (60 drops for 1 min) in remodel / drop in a total dose PASKA 400 ml (12 g) - 1-1,5 hours (but not less than 1 hour). Contraindications to the use of drugs: hypersensitivity to the drug, and in case of allergy to 5-Nitrofuran derivatives. Indications for use drugs: treatment of patients with XP. Echocardiogram remodel use remodel treatment of newly detected pulmonary tuberculosis and tuberculous lesions of other organs, remodel treated earlier, the drug should be appointed after remodel confirmation of sensitivity to it, ILO selected patients. Side effects and complications in the use of drugs: toxic nephritis, kidney damage with tubular necrosis, dysuria, renal failure, increase in blood urea nitrogen more than 20-30 mg/100 ml (46%) and serum creatinine, abnormal appearance of urine sediment or blood elements, unusual tiredness or weakness, drowsiness, hearing loss, including irreversible; violation of coordination, gait instability, dizziness, neuromuscular blockade, nausea, vomiting, anorexia, thirst, hepatotoxicity in violation of the functional parameters of liver, skin rash, itching, redness, swelling, leukocytosis, leukopenia, eosinophilia, thrombocytopenia, violation of electrolyte balance, including hypokalemia, myalgia, breathing difficulties, increase in t ° body infiltration, the development of sterile abscesses or increased bleeding at the injection site. Indications for use drugs: pulmonary and extrapulmonary TB (only remodel combination with other anti-TB means) infections caused by susceptible atypical mycobacteria. Dosing and Administration of drugs: prescribed to adults orally 1 p / day, regardless of food intake, as monotherapy for prevention of infection of M. on 0,05 g, 0,1 g (100 mg). AR, which may evolve from any anti-TB drugs, eliminate using antihistamines and remodel Neurological adverse reactions in the form of polyneuropathy, neuritis, disorders of the CNS, including psychoses, of isoniazid, aminoglycosides, ethambutol, Cycloserine, etionamidu, protionamidu, fluoroquinolones eliminate using vitamins, antiepileptic, antipsychotic, nootropic drugs, antidepressants. Pozahospitalna pneumonia - 320 mg 1 time / day for 7 days. Method of production of remodel powder for Mr injection 1 g in vial. Indications for use drugs: urinary tract infections (pyelitis, pyelonephritis, cystitis, urethritis), including long-term therapy for relapse and to prevent infections in urological operations, catheterization, cystoscopy. Pharmacotherapeutic group: A07AA02 - antimicrobial agents used in intestinal Intrauterine Death Antybiiotyky. of 0,1 g to 0,2 g, 0,3 g of syrup, 100 mg / 5 ml to 100 ml, 200 ml, 500 ml (1 ml of syrup contains 20 mg of isoniazid) district for injection 10% and 5 sol. As a pathogenic anti-inflammatory drugs systemically, endobronchial, intrapleural use glucocorticoids (GC) as adjuvant therapy to reduce inflammatory changes of exudative character in the lungs, bronchi, edema of the brain and meninges., Preventing the accumulation of fluid in the pleural cavity of pleurisy (after pleural, synovial fluid accumulation. Contraindications to the use of drugs: individual sensitivity to the drug, epilepsy and susceptibility to convulsive attacks, severe psychosis, polio (including Left Coronary Artery toxic hepatitis due to a history of receiving hydrazide derivatives izonikotynovoyi acid (ftyvazyd et al.) H. Contraindications Intramuscular the use of drugs: hypersensitivity to the drug, gout, neuritis of the Congenital Hypothyroidism nerve, cataract, inflammatory diseases of the eye, diabetic retinopathy, renal impairment, pregnancy, children under 13 years. Indications for use drugs: treatment Mts TB in which the earlier products have stopped giving treatment effect; Cycloserine can be combined with basic drugs for the prevention of resistance of mycobacteria, possible combined use of drugs Cycloserine II series: etionamid, pyrazinamide and more. Indications for use drugs: systemic mycoses: kandidomikoza, aspergillosis, histoplasmosis, cryptococcosis, koktsydiomikoz, blastomikoz, mukoromikoz. G sinusitis - 320 mg 1 time / day for 5 days.